The following parameters were used to assess exercise performance in the selected studies: creatine kinase (CK), lactic acid dehydrogenase, carbohydrate, fat, glycerol, malondialdehyde, enzymatic antioxidants, blood pH, taurine level, and muscular strength. Ten articles were retrieved, reviewed, and subjected to systematic analysis. In accordance with the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) statement, relevant articles were sought on PubMed, Medline, Web of Science, and Google Scholar using related terms, including taurine, exercise performance, exercise, muscle, physical training, running, strength, endurance exercise, resistance exercise, aerobic exercise, and swimming. Therefore, this review aimed to systematically review the dose response of taurine on both aerobic and strength exercise performance. However, how this molecule orchestrates such functions is unknown, particularly the dose response in exercised muscles. Taurine is a naturally occurring amino acid involved in various functions, including regulating ion channels, cell volume, and membrane stabilization. 4School of Health and Life Sciences, University of the West of Scotland, Blantyre, United Kingdom.3School of Agricultural Sciences and Rural Development (SASRD), Nagaland University, Medziphema, India.2Laboratory of Exercise Biochemistry in Health, Graduate Program in Health Sciences, School of Medicine, Pontifícia Universidade Católica do Paraná, Curitiba, Brazil.1Faculty of Sports Science, Ningbo University, Ningbo, China.Ugbolue 4, Anand Thirupathi 1 * and Yaodong Gu 1 * “And so maybe this is a tributary, not a fountain.Qi Chen 1, Zheng Li 1, Ricardo A. “I think there are going to be many tributaries of youth,” he says. Because aging is so complex, a singular fountain of youth probably doesn’t exist. “We’ve got a long way to go.”įinkel is circumspect, too. But lots of questions remain, he says, including what taurine actually does in the body and whether it works similarly in different animals, including people. As to whether taurine supplements improve people’s health, “we need to wait for a clinical trial,” Yadav says.įor now, taurine “is promising as a life span and health-span intervention,” says John Tower, a molecular biologist and geneticist who studies aging at the University of Southern California in Los Angeles who wasn’t involved in the study. In a separate experiment, an intense bout of exercise led to more taurine in people’s blood. Those links are correlations it’s not known whether low taurine had a part in causing those conditions. Yadav and his colleagues did look at data of nearly 12,000 people and found that individuals with obesity or diabetes had less taurine in their blood than people without the condition. There aren’t obvious, known risks of taurine, but thorough long-term studies at these high doses for people have not been done. The mice experiments used taurine levels that would be equivalent to about 3 or 6 grams per day for an adult human, Yadav says. Six middle-aged rhesus macaques fed extra taurine for six months seemed healthier, weighed less, had denser bones and showed signs of better metabolic health compared with five monkeys that didn’t get extra. Extra taurine led to improvements in aspects of bone strength, muscle coordination and memory in experiments with groups of five to 10 mice. Taurine was also linked with health in mice and female monkeys. elegans went from a median of almost 20 days to about 23 days on the highest doses tested. Taurine led to a similar life span boost for shorter-lived worms C. With taurine, that increased to nearly 33 months. For example, the median life span for female mice that didn’t get extra taurine was around 29 months. Molecular physiologist Vijay Yadav of Columbia University Irving Medical Center and colleagues found that extra taurine extended mice’s median life spans by 10 to 12 percent. Nevertheless, it has a range of suspected jobs in the body, from helping the developing brain to eye health to digestion. As far as amino acids go, taurine is an oddball: Unlike other more familiar amino acids, it doesn’t get incorporated into proteins. The results, 11 years in the making, center on taurine in part because scientists found its levels fall with age in the blood of mice, monkeys and humans. And this is a new set of findings that deserves to be followed up.” “So any way you can chip away at that edifice is great. Aging “is one of the great biological unknowns,” says biologist and cardiologist Toren Finkel of the University of Pittsburgh, who was not involved in the study.
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